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Article

Linkage of familial dysalbuminemic hyperthyroxinemia to the albumin gene in a large Amish kindred.

The Journal of clinical endocrinology and metabolism - 1 Jan 1995

Weiss R E, Sunthornthepvarakul T, Angkeow P, Marcus-Bagley D, Cox N, Alper C A, Refetoff S

Abstract excerpt

Familial dysalbuminemic hyperthyroxinemia (FDH) is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasians. Transmitted as an autosomal dominant trait, it is always associated with high serum total T4 (TT4) and more rarely with elevated total T3 (TT3) and/or rT3 (TrT3) concentrations. Free T4, by dialysis, and TSH levels are normal, suggesting the presence of a T4-binding protein abnormality....

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PMID: 7829599
DOI: 10.1210/jcem.80.1.7829599

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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