Article
Linkage of familial dysalbuminemic hyperthyroxinemia to the albumin gene in a large Amish kindred.
The Journal of clinical endocrinology and metabolism - 1 Jan 1995
Weiss R E, Sunthornthepvarakul T, Angkeow P, Marcus-Bagley D, Cox N, Alper C A, Refetoff S
Abstract excerpt
Familial dysalbuminemic hyperthyroxinemia (FDH) is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasians. Transmitted as an autosomal dominant trait, it is always associated with high serum total T4 (TT4) and more rarely with elevated total T3 (TT3) and/or rT3 (TrT3) concen...
Topics
- Base Sequence
- Child, Preschool
- Ethnicity
- Female
- Genetic Linkage
- Haplotypes
- Humans
- Hyperthyroxinemia
- Molecular Probes
- Molecular Sequence Data
- Pedigree
- Phenotype
- Serum Albumin
- Thyroxine
- Triiodothyronine, Reverse