Location and PCR-based detection of three polymorphisms of the human erythrocyte beta-spectrin gene (SPTB).

doi:10.1111/j.1365-2141.1994.tb05043.x

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Article

Location and PCR-based detection of three polymorphisms of the human erythrocyte beta-spectrin gene (SPTB).

British journal of haematology - 1 Oct 1994

Gallagher P G, Lecomte M C, Galand C, Wang Y P, Tse W T, Forget B G

Abstract excerpt

Defects of beta spectrin, a structural protein of the erythrocyte membrane skeleton, have been identified in many cases of inherited disorders of red blood cell shape such as hereditary elliptocytosis and spherocytosis. To aid in genetic analyses of families with these disorders, the locations of...

Topics

Alleles
Base Sequence
Elliptocytosis, Hereditary
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Genetic
Spectrin
Spherocytosis, Hereditary

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