Article
A genetic analysis of the 63E-64A genomic region of Drosophila melanogaster: identification of mutations in a replication factor C subunit.
Genetics - 1 Apr 1995
Harrison S D, Solomon N, Rubin G M
Abstract excerpt
We have performed an F2 genetic screen to identify lethal mutations within the 63E-64A genomic region. We have isolated 122 mutations in 20 different complementation groups. Of these groups, 16 are represented by multiple alleles. We have also established that the Rop and Ras2 genes are located w...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA Replication
- DNA-Binding Proteins
- Drosophila melanogaster
- Genes, Insect
- Genes, Lethal
- Genetic Complementation Test
- Heterozygote
- Homeodomain Proteins
- Homozygote
- Minor Histocompatibility Antigens
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- Proto-Oncogene Proteins c-bcl-2
- Replication Protein C