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Article

Characterization of Two Second Messenger Pathways and Their Interactions in Eliciting the Human Sperm Acrosome Reaction

2 Jan 1995

Abstract excerpt

The human sperm acrosome reaction (AR) occurs via the activation of at least two signal transduction pathways. The purpose of this investigation was to characterize two of the pathways, the protein kinase A (PKA) and C (PKC) pathways, and determine whether pathway "crosstalk" occurs between them in eliciting the AR in capacitated spermatozoa. Stimulators of each pathway were tested in a dose-dependent manner....

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PMID: 7768751
DOI: 10.1002/j.1939-4640.1995.tb01728.x

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