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Article

EGF, TGF-α and EGFR expression in human preimplantation embryos

1 Feb 1995

Abstract excerpt

ABSTRACT Epidermal growth factor (EGF) and transforming growth factor alpha (TGF-α) through their common receptor, epidermal growth factor receptor (EGFR) are known to enhance mitogenesis, development and implantation in several species. In the mouse, co-culture of grouped embryos in microdrops increases the cell number and pro-portion developing to the blastocyst stage. A similar effect is observed with culture...

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PMID: 7768173
DOI: 10.1242/dev.121.2.299

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