Article
Monozygotic twins with facioscapulohumeral dystrophy (FSHD): implications for genotype/phenotype correlation. FSH-DY Group.
Muscle & nerve. Supplement - 1 Jan 1995
Griggs R C, Tawil R, McDermott M, Forrester J, Figlewicz D, Weiffenbach B
Abstract excerpt
Facioscapulohumeral dystrophy (FSHD) is an autosomal-dominant disorder with a characteristic and distinctive distribution of weakness but a high degree of variation in the age of onset and rate of progression. Monozygotic twins provide the opportunity to assess the relative importance of genetic as opposed to nongenetic influences on the course of disease. We have studied three sets of monozygotic twins with FSHD...
Topics
- Adult
- Face
- Genotype
- Humans
- Humerus
- Middle Aged
- Muscular Dystrophies
- Phenotype
- Scapula
- Twins, Monozygotic