Article
Tuberous sclerosis.
Dermatologic clinics - 1 Jan 1995
Roach E S, Delgado M R
Abstract excerpt
Tuberous sclerosis complex is a disorder of cellular differentiation and proliferation that is inherited as an autosomal dominant trait with variable penetrance and a high spontaneous mutation rate. Lesions occur in the brain, skin, kidneys, heart, and other organs. Recent studies suggest genetic heterogeneity, with at least two gene loci on chromosomes 9, 16, and perhaps 11.
Topics
- Cell Differentiation
- Cell Division
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- Chromosomes, Human, Pair 16
- Chromosomes, Human, Pair 9
- Humans
- Mutation
- Precancerous Conditions
- Tuberous Sclerosis