Article
An apolipoprotein CIII marker associated with hypertriglyceridemia in Caucasians also confers increased risk in a west Japanese population.
Human genetics - 1 Apr 1995
Zeng Q, Dammerman M, Takada Y, Matsunaga A, Breslow J L, Sasaki J
Abstract excerpt
Polymorphisms and haplotypes at the adjacent apolipoprotein (apo) AI and CIII gene loci were investigated in 61 Japanese patients with triglycerides greater than 350 mg/dl and in 66 unrelated normolipidemic subjects. The polymorphic sites were the SstI site in the apoCIII 3' untranslated region, whose presence has previously been shown to be associated with hypertriglyceridemia (HTG) in Caucasians, and the MspI...
Topics
- Alleles
- Apolipoprotein A-I
- Apolipoprotein C-III
- Apolipoproteins C
- Base Sequence
- DNA Primers
- Female
- Gene Frequency
- Genetic Markers
- Haplotypes
- Humans