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Article

Detection of two point mutations causing familial defective apolipoprotein B-100 by heteroduplex analysis.

Molecular and cellular probes - 1 Dec 1994

Kotze M J, Langenhoven E, Peeters A V, Theart L, Oosthuizen C J

Abstract excerpt

Familial defective apolipoprotein B-100 (FDB) is a dominantly-inherited genetic disorder causing primary hypercholesterolemia and premature coronary heart disease. To date, only two mutations causing FDB have been identified. A rapid non-radioactive technique is described to detect both disease-related apolipoprotein B point mutations in polymerase chain reaction (PCR) products amplified from genomic DNA....

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Source

Identifiers

PMID: 7700273
DOI: 10.1006/mcpr.1994.1072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Detection of two point mutations causing familial defective apolipoprotein B-100 by heteroduplex analysis.PMID 7700273Read ↗

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