Use of automated sequencing of polymerase chain reaction-generated amplicons to identify three types of cholera toxin subunit B in Vibrio cholerae O1 strains.

doi:10.1128/jcm.31.1.22-25.1993

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Article

Use of automated sequencing of polymerase chain reaction-generated amplicons to identify three types of cholera toxin subunit B in Vibrio cholerae O1 strains.

Journal of clinical microbiology - 1 Jan 1993

Olsvik O, Wahlberg J, Petterson B, Uhlén M, Popovic T, Wachsmuth I K, Fields P I

Abstract excerpt

Cholera toxin is the principal factor causing the profuse intestinal fluid secretion that is characteristic of cholera. The DNA sequences of the cholera toxin subunit B structural genes from 45 Vibrio cholerae O1 strains isolated in 29 countries over a period of 70 years were determined by automa...

Topics

Africa
Americas
Asia
Australia
Base Sequence
Cholera
Cholera Toxin
DNA, Bacterial
Genes, Bacterial
Genetic Variation
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Sequence Analysis, DNA
Vibrio cholerae

Source

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Identifiers

PMID: 7678018
DOI: 10.1128/jcm.31.1.22-25.1993
PMCID: PMC262614

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7678018-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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