Article
In vitro establishment and characterization of two acquired immunodeficiency syndrome-related lymphoma cell lines (BC-1 and BC-2) containing Kaposi's sarcoma-associated herpesvirus-like (KSHV) DNA sequences.
Blood - 1 Oct 1995
Cesarman E, Moore P S, Rao P H, Inghirami G, Knowles D M, Chang Y
Abstract excerpt
Two unique DNA fragments were recently identified in over 90% of acquired immunodeficiency syndrome (AIDS)-related Kaposi's sarcoma tissues. Sequence analysis suggests that these fragments belong to a previously unidentified human herpesvirus, Kaposi's sarcoma-associated herpesvirus (KSHV). These fragments have also been identified in a subset of non-Hodgkin's lymphomas in human immunodeficiency virus-positive...
Topics
- Base Sequence
- Blotting, Southern
- Cell Nucleus
- Cytoplasm
- DNA Restriction Enzymes
- DNA, Viral
- Genotype
- Humans
- Immunophenotyping
- In Situ Hybridization
- Lymphoma, AIDS-Related