Article
Clinical and prognostic evaluation of familial hypertrophic cardiomyopathy in two South African families with different cardiac beta myosin heavy chain gene mutations.
British heart journal - 1 Jul 1995
Posen B M, Moolman J C, Corfield V A, Brink P A
Abstract excerpt
BACKGROUND: Familial hypertrophic cardiomyopathy is the most common inherited cardiac disorder, with sudden cardiac death at a young age the most frequent cause of death in affected individuals. Some cases of familial hypertrophic cardiomyopathy are caused by missense mutations of the beta myosin...
Topics
- Adolescent
- Adult
- Aged
- Base Sequence
- Cardiomyopathy, Hypertrophic
- Child
- Child, Preschool
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Myosins
- Pedigree
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational