Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nonindependence of matches at different loci in DNA profiles: quantifying the effect of close relatives on the match probability.

Heredity - 1 Jul 1995

Donnelly P

Abstract excerpt

In comparing a particular DNA profile with that from an unknown (but distinct) individual, matches at different loci between the profiles will not be independent, even in a randomly mating population, because of the presence in the population of relatives of the individuals. The paper contains a theoretical analysis of the extent of this effect on the match probability, for profiling techniques which separately...

Topics

Alleles
DNA Fingerprinting
DNA Probes
Female
Genotype
Humans
Interpersonal Relations
Linkage Disequilibrium
Male
Minisatellite Repeats
Models, Genetic
Probability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7649755
DOI: 10.1038/hdy.1995.100

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7649755-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nonindependence of matches at different loci in DNA profiles: quantifying the effect of close relatives on the match probability.PMID 7649755Read ↗

Match probability calculations for multi-locus DNA profiles.Semantic proximity Read ↗

Assessing the evidential value of DNA profiles matching without using the assumption of independent loci.Semantic proximity Read ↗

DNA profile match probability calculation: how to allow for population stratification, relatedness, database selection and single bands.Semantic proximity Read ↗

A two-locus forensic match probability for subdivided populations.Semantic proximity Read ↗

DNA profile match probabilities in a subdivided population: when can subdivision be ignored?Semantic proximity Read ↗

Population genetics of coincidental DNA matches.Semantic proximity Read ↗

Adventitious match probability for autosomal profiles when primer binding site mutation is possible.Semantic proximity Read ↗

On the consequences of DNA profile mismatches for close relatives of an excluded suspect.Semantic proximity Read ↗

Does an English appeal court ruling increase the risks of miscarriages of justice when complex DNA profiles are searched against the national DNA database?Semantic proximity Read ↗

How high should paternity index be for reliable identification of war victims by DNA typing?Semantic proximity Read ↗

The effect of relatedness on likelihood ratios and the use of conservative estimates.Semantic proximity Read ↗

Partial matches in heterogeneous offender databases do not call into question the validity of random match probability calculations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.