Article
Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11.
Proceedings of the National Academy of Sciences of the United States of America - 15 Aug 1995
Karayiorgou M, Morris M A, Morrow B, Shprintzen R J, Goldberg R, Borrow J, Gos A, Nestadt G, Wolyniec P S, Lasseter V K
Abstract excerpt
We report the results of two studies examining the genetic overlap between schizophrenia and velocardiofacial syndrome. In study A, we characterize two interstitial deletions identified on chromosome 22q11 in a sample of schizophrenic patients. The size of the deletions was estimated to be between 1.5 and 2 megabases. In study B, we examine whether variations in deletion size are associated with the schizophrenic...
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