Article
Molecular and clinical correlations in spinocerebellar ataxia type 3 and Machado-Joseph disease.
Annals of neurology - 1 Jul 1995
Matilla T, McCall A, Subramony S H, Zoghbi H Y
Abstract excerpt
The autosomal dominant spinocerebellar ataxias are clinically and genetically a heterogeneous group of neurodegenerative disorders. Genetic studies have classified some of these disorders based on the mapping of their respective genes. The gene for Machado-Joseph disease, one type of spinocerebel...
Topics
- Adolescent
- Adult
- Age of Onset
- Alleles
- Base Sequence
- DNA
- Female
- Humans
- Machado-Joseph Disease
- Male
- Middle Aged
- Molecular Sequence Data
- Polymerase Chain Reaction
- Repetitive Sequences, Nucleic Acid
- Spinocerebellar Degenerations