[Clinical applications of molecular diagnosis of retinoblastoma ain 15 families].

doi:10.1055/s-2008-1035456

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Article

[Clinical applications of molecular diagnosis of retinoblastoma ain 15 families].

Klinische Monatsblatter fur Augenheilkunde - 1 May 1995

Lendi B, Pescia G, Thonney F, Balmer A, Munier F

Abstract excerpt

PURPOSE: In 40% retinoblastoma (Rb) results from a hereditary mutation of the Rb susceptibility gene (RB1). In this study, we tested the usefulness of intragenic DNA analysis for ophthalmologic follow-up in affected families. METHODS: Molecular analysis was performed on 103 DNA samples of 15 Rb f...

Topics

Adult
Alleles
Child
DNA Mutational Analysis
Eye Neoplasms
Female
Genetic Carrier Screening
Genetic Counseling
Humans
Infant
Male
Pedigree
Polymorphism, Restriction Fragment Length
Retinoblastoma
Risk Factors

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