Article
Lack of a high prevalence of the BB vitamin D receptor genotype in severely osteoporotic women.
The Journal of clinical endocrinology and metabolism - 1 Jul 1995
Looney J E, Yoon H K, Fischer M, Farley S M, Farley J R, Wergedal J E, Baylink D J
Abstract excerpt
Studies of twins strongly suggest that more than 50% of the peak spinal bone density is determined by genetics. It was reported recently that this genetic effect is primarily determined by vitamin D receptor (VDR) alleles; specifically, a VDR genotype termed BB has been highly associated with low peak bone density. Homozygotes for the second VDR allele, bb, are associated with high peak bone density. If peak bone...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.