Article
Lack of a high prevalence of the BB vitamin D receptor genotype in severely osteoporotic women.
The Journal of clinical endocrinology and metabolism - 1 Jul 1995
Looney J E, Yoon H K, Fischer M, Farley S M, Farley J R, Wergedal J E, Baylink D J
Abstract excerpt
Studies of twins strongly suggest that more than 50% of the peak spinal bone density is determined by genetics. It was reported recently that this genetic effect is primarily determined by vitamin D receptor (VDR) alleles; specifically, a VDR genotype termed BB has been highly associated with low...
Topics
- Age Factors
- Aged
- Alleles
- Blotting, Southern
- DNA, Complementary
- Female
- Genetic Carrier Screening
- Genotype
- Homozygote
- Humans
- Osteoporosis
- Predictive Value of Tests
- Receptors, Calcitriol
- Restriction Mapping
- Risk Factors