Demonstration of either endogenous recurrence or exogenous reinfection by restriction endonuclease cleavage analysis of herpes simplex virus from patients with recrudescent genital herpes.

doi:10.1002/jmv.1890460416

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Article

Demonstration of either endogenous recurrence or exogenous reinfection by restriction endonuclease cleavage analysis of herpes simplex virus from patients with recrudescent genital herpes.

Journal of medical virology - 1 Aug 1995

Sakaoka H, Aomori T, Gouro T, Kumamoto Y

Abstract excerpt

By using restriction endonuclease (RE) cleavage analysis, either endogenous recurrence or exogenous reinfection of herpes simplex virus (HSV) was clarified in 45 male and 20 female subjects with recrudescent genital herpes. All of the plural (two to ten) isolates from 63 (205 isolates) out of 65 subjects (97%) were HSV-2. Two isolates from only one of 65 subjects (1.5%) were HSV-1, and they showed the same RE...

Topics

Adult
Aged
Animals
Chlorocebus aethiops
Female
Genotype
Herpes Genitalis
Herpes Simplex
Herpesvirus 1, Human
Herpesvirus 2, Human
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Recurrence

Restriction Mapping

Vero Cells

Virus Activation

Source

Open in PubMed

Identifiers

PMID: 7595418
DOI: 10.1002/jmv.1890460416

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7595418-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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