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Article

Site-directed replacement of the coaxial heme ligands of bacterioferritin generates heme-free variants.

The Journal of biological chemistry - 6 Oct 1995

Andrews S C, Le Brun N E, Barynin V, Thomson A J, Moore G R, Guest J R, Harrison P M

Abstract excerpt

The bacterioferritin (BFR) of Escherichia coli is a heme-containing iron storage molecule. It is composed of 24 identical subunits, which form a roughly spherical protein shell surrounding a central iron storage cavity. Each of the 12 heme moieties of BFR possesses bis-methionine axial ligation, a heme coordination scheme so far only found in bacterioferritins. Members of the BFR family contain three partially...

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Identifiers

PMID: 7559480
DOI: 10.1074/jbc.270.40.23268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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