Alpha 1-antitrypsin deficiency and chronic pancreatitis.

doi:10.1007/BF02208669

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Alpha 1-antitrypsin deficiency and chronic pancreatitis.

Digestive diseases and sciences - 1 Sept 1995

Rabassa A A, Schwartz M R, Ertan A

Abstract excerpt

Alpha 1-antitrypsin deficiency is a genetic disorder commonly associated with pulmonary and hepatic injury. Low serum levels of this glycoprotein result in an imbalance between circulating protease and protease inhibitors, which is thought to play a role in the development of emphysema. In recent studies, a protease-to-protease inhibitor imbalance in patients with alpha 1-antitrypsin deficiency was thought to be...

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