Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

KAL, a gene mutated in Kallmann's syndrome, is expressed in the first trimester of human development.

Molecular and cellular endocrinology - 28 Apr 1995

Duke V M, Winyard P J, Thorogood P, Soothill P, Bouloux P M, Woolf A S

Abstract excerpt

Kallmann's syndrome (KS) is characterised by the association of anosmia and isolated hypogonadotrophic hypogonadism (IHH). Mutations of the KAL gene which is located at Xp22.3 cause X-linked KS (XKS). In this study we used the reverse transcriptase polymerase chain reaction and in situ hybridisation to examine the developmental expression of KAL in the first trimester of pregnancy, the earliest stage of human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Gene Expression
Share to In Situ Hybridization

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Polymerase Chain Reaction

Share to Pregnancy

Share to RNA, Messenger

Source

Identifiers

PMID: 7545624
DOI: 10.1016/0303-7207(95)03518-c

Genes

IHH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

KAL, a gene mutated in Kallmann's syndrome, is expressed in the first trimester of human development.PMID 7545624Read ↗

X-linked GnRH deficiency: role of KAL-1 mutations in GnRH deficiency.Semantic proximity Read ↗

A molecular approach to the pathophysiology of the X chromosome-linked Kallmann's syndrome.Semantic proximity Read ↗

Diversity in fibroblast growth factor receptor 1 regulation: learning from the investigation of Kallmann syndrome.Semantic proximity Read ↗

FGFR1 mutations in Kallmann syndrome.Semantic proximity Read ↗

The Importance of Autosomal Genes in Kallmann Syndrome: Genotype-Phenotype Correlations and Neuroendocrine CharacteristicsSemantic proximity Read ↗

The importance of autosomal genes in Kallmann syndrome: genotype-phenotype correlations and neuroendocrine characteristics.Semantic proximity Read ↗

X chromosome-linked Kallmann syndrome: clinical heterogeneity in three siblings carrying an intragenic deletion of the KAL-1 gene.Semantic proximity Read ↗

Anosmin-1 is a regionally restricted component of basement membranes and interstitial matrices during organogenesis: Implications for the developmental anomalies of X chromosome-linked Kallmann syndromeSemantic proximity Read ↗

The complex genetics of Kallmann syndrome: KAL1, FGFR1, FGF8, PROKR2, PROK2, et al.Semantic proximity Read ↗

Familial Kallmann syndrome: a novel splice acceptor mutation in the KAL gene.Semantic proximity Read ↗

Kallmann syndrome with FGFR1 and KAL1 mutations detected during fetal lifeSemantic proximity Read ↗

A recurrent missense mutation in the KAL gene in patients with X-linked Kallmann's syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.