Article
[Molecular-genetic analysis of certain mutations of the "cystic fibrosis gene" in Moldavia. Characteristics of molecular markers and their linkage with various mutations].
Genetika - 1 Dec 1994
Gimbovskaia S D, Kalinin V N, Ivashchenko T E, Baranov V S
Abstract excerpt
Sixty-one patients with cystic fibrosis (CF) from Moldova were tested for mutations delta F508, G551D, and R553X. Frequencies of various alleles of the repeated GATT sequence in intron 6B of the CFTR gene, their linkage to other polymorphic markers, and various mutations were determined. The freq...
Topics
- Base Sequence
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- DNA Primers
- Genetic Linkage
- Haplotypes
- Humans
- Membrane Proteins
- Moldova
- Molecular Sequence Data
- Mutation
- Pancreas