Normal sweat chloride values do not exclude the diagnosis of cystic fibrosis.

Abstract excerpt

Since its introduction in 1959, the sweat test has remained the "gold standard" diagnostic test for cystic fibrosis (CF). It is apparent that CF encompasses a wide spectrum of disease, from meconium ileus and severe respiratory compromise in infants to the presentation of mild pulmonary symptoms and no evidence of gastrointestinal disease in adults. In patients with lung disease that might otherwise be consistent...

Topics

• Adult
• Chlorides
• Cystic Fibrosis
• Cystic Fibrosis Transmembrane Conductance Regulator
• Female
• Heterozygote
• Humans
• Male
• Membrane Proteins
• Mutation
• Pedigree