Article
Genetic linkage of proteolipid protein (PLP) and thyroxine-binding globulin (TBG) on the ovine X chromosome.
Cytogenetics and cell genetics - 1 Jan 1994
Sise J A, Hanrahan V, Montgomery G W, Hill D F
Abstract excerpt
Restriction fragment length polymorphisms (RFLPs) demonstrating X-linked inheritance have been identified for proteolipid protein (PLP) and thyroxine-binding globulin (TBG) in sheep. Genetic linkage between ovine PLP and TBG was examined in a three-generation flock containing 122 individuals. Significant linkage between the loci was observed with a combined lod score of 7.48 at a recombination fraction of 5 cM.
Topics
- Alleles
- Animals
- DNA
- Female
- Gene Frequency
- Genetic Linkage
- Male
- Myelin Proteins
- Myelin Proteolipid Protein
- Pedigree
- Polymorphism, Restriction Fragment Length