Article
A tactile sensory system of Myxococcus xanthus involves an extracellular NAD(P)(+)-containing protein.
Genes & development - 1 Dec 1995
Lee B U, Lee K, Mendez J, Shimkets L J
Abstract excerpt
CsgA is a cell surface protein that plays an essential role in tactile responses during Myxococcus xanthus fruiting body formation by producing the morphogenic C-signal. The primary amino acid sequence of CsgA exhibits homology with members of the short-chain alcohol dehydrogenase (SCAD) family and several lines of evidence suggest that NAD(P)+ binding is essential for biological activity. First, the predicted...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Binding Sites
- Carrier Proteins
- Fatty Acid Desaturases
- Maltose-Binding Proteins
- Models, Biological
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
