Article
[Mutagenic effects of gamma-rays on plasmid DNA in Escherichia coli].
Radiobiologiia - 1 Jan 2000
Kalinin V L, Suslova I N, Suslov A V
Abstract excerpt
A purified and dried DNA of plasmid pKO482 (galK+) is 10 times more resistant to the inactivating action of 60Co-gamma-rays than that of lambda phage. gamma-Irradiation of the plasmid DNA induces forward mutations of galK, the frequency of which increases linearly with the dose. The efficiency of the mutagenic action of gamma-rays on the plasmid galK locus is 10(-12) per 1 rad and per 1 base pair. The mutagenic...
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