[Biological effectiveness of ionizing radiations of various quality in Escherichia coli bacteria (a theoretical analysis). A cell inactivation model].

Abstract excerpt

The dependence of the radiosensitivity of bacteria (the wild type, superresistant and rec-mutants) on linear energy transfer (LET) is considered. A nonformal model of inactivation of different bacterial mutants has been developed on the basis of the experimental data available. The concept of "metastable siles" (MS) is introduced. MS are peculliar DNA lesions arising from the occurrence of large nucleolytic gaps...

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