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Article

Glucose-TOR-PDCB signaling restricts cell-to-cell communication through callose deposition.

Science advances - 4 Sept 2026

Busche Michael, Runkel Anne M, Xu Min, Klimpel Katherine A, Menon Sannidhi, Lund Katherine M, Koch Kyle, Chatterjee Snigdha, Alberts Erin R, Martinez Ryan E, Scarpin M Regina, Brunkard Jacob O

Abstract excerpt

Plant cells are connected by plasmodesmata (PD), membrane-lined channels that facilitate cell-to-cell transport. Forward genetic screens to uncover regulators of PD transport identified mutants with increased (ise1 to ise4) or decreased (dse1) PD trafficking during embryogenesis. Despite their opposite effects on PD transport, we found that the transcriptional profiles of dse1, ise3, and ise4 were notably similar...

Read the complete abstract on PubMed

Topics

Glucans
Signal Transduction
Plasmodesmata
Arabidopsis Proteins
Arabidopsis
Cell Communication

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Glucose

Gene Expression Regulation, Plant

Basic-Leucine Zipper Transcription Factors

TOR Serine-Threonine Kinases

Mutation

Phosphatidylinositol 3-Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 42696584
DOI: 10.1126/sciadv.aeg9566
PMCID: PMC13544204

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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