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Article

T Cell Phenotype Influences Acoustofluidic Delivery of Biomolecules.

Ultrasound in medicine & biology - 1 Nov 2026

Colebank Madison C, Sarkar Omar Sadi, Chew Lewis, Yaddanapudi Kavitha, Kopechek Jonathan A

Abstract excerpt

OBJECTIVE: Ultrasound-mediated sonoporation has been explored for intracellular delivery in T cells, yet most studies rely on immortalized cell lines, limiting translational relevance. This study aimed to directly compare acoustofluidic molecular delivery efficiency and intracellular distribution in Jurkat T cells and primary human T cells. METHODS: Ultrasound-mediated molecular delivery was assessed using...

Read the complete abstract on PubMed

Topics

Humans
Jurkat Cells
Dextrans
T-Lymphocytes
Microbubbles
Phenotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 42674881
DOI: 10.1016/j.ultrasmedbio.2026.06.026

Genes

CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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