Does the AMPD1 C34T Polymorphism Influence Physical Performance in Elite Athletes?

doi:10.3390/genes17080935

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Does the AMPD1 C34T Polymorphism Influence Physical Performance in Elite Athletes?

Genes - 11 Aug 2026

Martin Daniel R, Stebbings Georgina K, Heffernan Shane M, Erskine Robert M, Antrobus Mark, Brazier Jon, Lockey Sarah, Jackson Alex L, Day Stephen, Kilduff Liam, Bennett Mark, Raleigh Stuart M, Cullen Tom, Collins Malcolm, Pitsiladis Yannis, Callus Peter, Herbert Adam J, Williams Alun G

Abstract excerpt

Background/Objectives: Adenosine monophosphate deaminase deficiency has been implicated in impaired exercise capacity. We examined whether the AMPD1 C34T (rs17602729) genotype was associated with athlete status and performance in distance runners (DRs) and rugby union (RU) athletes. Methods: Participants included 621 elite male RU athletes, 666 elite/sub-elite male and female DRs, and 1029 male and female...

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Alleles
AMP Deaminase
Athletes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Athletic Performance

Gene Frequency

Genotype

Polymorphism, Single Nucleotide

Running

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Open in PubMed Open full text

Identifiers

PMID: 42650127
DOI: 10.3390/genes17080935
PMCID: PMC13512766

Genes

AMPD1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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