ESL-PSC Toolkit: a graphical software environment for linking shared genetic changes to convergent phenotypes.

doi:10.1093/molbev/msag205

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ESL-PSC Toolkit: a graphical software environment for linking shared genetic changes to convergent phenotypes.

Molecular biology and evolution - 1 Aug 2026

Allard John B, Kumar Sudhir

Abstract excerpt

Convergent evolution provides a useful framework for testing whether independent origins of similar traits share common genetic mechanisms. Evolutionary Sparse Learning with Paired Species Contrast (ESL-PSC) is an approach to identify genes and sites associated with convergent traits from aligned sequences by fitting sparse predictive models to phylogenetically informed species contrasts. However, practical use...

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Computational Biology
Computer Graphics
Evolution, Molecular
Phenotype
Phylogeny
Software
User-Computer Interface

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PMID: 42585597
DOI: 10.1093/molbev/msag205
PMCID: PMC13511134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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