Identification of a hypervirulent extensively drug-resistant ST383 Klebsiella pneumoniae sub-lineage carrying ICEKp5 in Lebanon.

doi:10.1128/aac.00384-26

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Identification of a hypervirulent extensively drug-resistant ST383 Klebsiella pneumoniae sub-lineage carrying ICEKp5 in Lebanon.

Antimicrobial agents and chemotherapy - 2 Sept 2026

Abboud Martine, Chaaya Tia Clara, Daccache Yara, Alam Nour El, Gerges Theresa, Haddad Lea, Kassabian Leon, Tannous Jame, Ghanem Yara, Nabbout Judy, Chaar Kevin, Nmeir Toni, Haddad Anthony, Al Khoury Charbel, Araj George F, Tokajian Sima

Abstract excerpt

Klebsiella pneumoniae ST383 has emerged as a high-risk clone, characterized by carbapenem resistance and increasing detection of hypervirulence determinants. We describe a phylogenetically distinct ST383 sub-lineage in Lebanon, defined by the acquisition of ICEKp5, which carries the yersiniabactin locus. Three ST383 K. pneumoniae clinical isolates (LBN_CAKp91, LBN_CTKp3, and LBN_CTKp11) recovered from a Lebanese...

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Topics

Klebsiella pneumoniae
Lebanon
Drug Resistance, Multiple, Bacterial
Anti-Bacterial Agents

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Humans

Phylogeny

Microbial Sensitivity Tests

Polymorphism, Single Nucleotide

Klebsiella Infections

Thiazoles

Bacterial Proteins

beta-Lactamases

Whole Genome Sequencing

Carbapenems

Virulence

Phenols

Source

Open in PubMed

Identifiers

PMID: 42554642
DOI: 10.1128/aac.00384-26

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