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Article

Introducing the TOP framework: a novel phenotyping solution for collaborative phenotype algorithm development and application.

Journal of biomedical semantics - 27 Jul 2026

Beger Christoph, Strobach Dorothea, Schäfermeier Ralph, Matthies Franz, Höffner Konrad, Uciteli Alexandr

Abstract excerpt

BACKGROUND: Phenotyping, the comprehensive assessment of observable characteristics, is essential for advancing medical understanding and personalised healthcare. However, traditional phenotyping methods are often manual, time-intensive, and limited in scope. To address these challenges, this work introduces the TOP Framework, a software suite that leverages a structured approach. It provides tools for the formal...

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PMID: 42538550
DOI: 10.1186/s13326-026-00364-7
PMCID: PMC13428426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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