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Comprehensive Analysis of Mutations in the Hepatitis Delta Virus Genome Based on Full-Length Sequencing in Individuals Infected with Genotype 3 in Brazil.

Archives of virology - 30 Jul 2026

Roca Tárcio Peixoto, da Silva Queiroz Jackson Alves, Passos-Silva Ana Maisa, da Silva Mayara Torquato Lima, de Castro-Silva Eugênia, Borzacov Lourdes Maria Pinheiro, Villalobos-Salcedo Juan Miguel, Vieira Deusilene, Villar Livia Melo

Abstract excerpt

HDV has a high genetic diversity among isolates and a high capacity to accumulate mutations over time. The mechanisms involved in the clinical progression of HDV are not fully elucidated. Few studies relate mutations to clinical implications, which makes this variable extremely relevant for research into HDV-3, a genotype associated with worse clinical progression. The aim of this study was to analyze mutations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42533182
DOI: 10.1007/s00705-026-06697-z
PMCID: PMC13424809

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