Article
Hypermutability of integrated sequences of viral origin in a chlorarachniophyte.
Proceedings of the National Academy of Sciences of the United States of America - 4 Aug 2026
Mettrop Lisa, Lipzen Anna, Mirambeau Gilles, Barry Kerrie, Grigoriev Igor V, Piganeau Gwenaël, Krasovec Marc
Abstract excerpt
Mutations provide the raw material for evolution, but mutation rates are not uniform across genomes. Using a mutation accumulation experiment in the marine phytoplankton Bigelowiella natans, we found extreme local variation in mutation rate: over 1,000-fold differences across its nuclear genome. While the baseline single-nucleotide mutation rate is approximately 3.5 × 10-10 per site per generation, a common value...
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