Transdiagnostic monoamine-based subtyping for attention-deficit/hyperactivity disorder and autism spectrum disorder via unsupervised machine learning.

Abstract excerpt

Neuroimaging and molecular studies have examined the etiology of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). However, their findings remain inconsistent because of within-disorder heterogeneity and cross-disorder phenotypic overlap. We sought to identify monoamine-based subtypes across ADHD and ASD and clarify their brain structural characteristics. In 83 children with ADHD...

Topics

• Humans
• Attention Deficit Disorder with Hyperactivity
• Unsupervised Machine Learning
• Male
• Autism Spectrum Disorder