Rethinking soil-transmitted helminth diagnostics in the genomic era: Does genetic variation matter?

Abstract excerpt

Soil-transmitted helminths (STHs) are intestinal parasitic worms that present a significant global health challenge. Traditionally, the diagnosis of STH infections has relied on microscopy; however, molecular tests such as quantitative PCR (qPCR) are now widely adopted for their greater sensitivity, increasingly reduced cost and higher throughput. Recent evidence highlights genetic diversity in both coding and...

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