A comparative analysis of the clinical and genomic characteristics of Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus in Korea and Japan.

doi:10.1128/spectrum.00589-26

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A comparative analysis of the clinical and genomic characteristics of Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus in Korea and Japan.

Microbiology spectrum - 1 Sept 2026

Kaneko Hiroshi, Kim Eu Suk, Yokomori Shiho, Park Wan Beom, Jung Jongtak, Moon Song Mi, Song Kyoung-Ho, Park Jeong Su, Kim Taek Soo, Hirai Yuji, Maruyama Hiroshi, Kamimura Mitsuhiro, Miura Hiroyuki, Tsuchiya Kayoko, Kim Hong Bin, Nakaminami Hidemasa

Abstract excerpt

Panton-Valentine leukocidin (PVL) is a leukocyte-lytic toxin produced by Staphylococcus aureus, which is primarily associated with skin and soft tissue infections. Notably, there has been an increase in the number of cases caused by the USA300 lineage in Japan. However, the reported prevalence of USA300 is limited in other Asian countries, including Korea. This study investigated the prevalence of PVL-positive...

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Topics

Leukocidins
Exotoxins
Bacterial Toxins
Methicillin-Resistant Staphylococcus aureus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Humans

Japan

Republic of Korea

Staphylococcal Infections

Phylogeny

Molecular Epidemiology

Genotype

Virulence Factors

Bacterial Proteins

Source

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Identifiers

PMID: 42478847
DOI: 10.1128/spectrum.00589-26
PMCID: PMC13532211

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