Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical phenotypes of epigenetic biomarker positive versus biomarker negative postpartum depression.

Journal of affective disorders - 1 Dec 2026

Wenzel Elizabeth S, Kaminsky Zachary, Pennycuff Kayla, Pangtey Meeta, Payne Jennifer L

Abstract excerpt

Postpartum depression (PPD) can be predicted by biomarkers of 3rd trimester methylation at two estrogen-responsive genes (TTC9B, HP1BP3), but the mechanism(s) by which these epigenetic changes lead to PPD are unknown. We investigated whether clinical characteristics (psychiatric histories, depression onset, stress/anxiety/trauma) differ between those with (BM+) and without (BM-) these biomarkers of PPD risk....

Read the complete abstract on PubMed

Topics

Humans
Female
Depression, Postpartum
Biomarkers
Adult
Pregnancy
Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Phenotype

Pregnancy Trimester, Third

Anxiety

Stress, Psychological

DNA Methylation

Source

Open in PubMed Open full text

Identifiers

PMID: 42476341
DOI: 10.1016/j.jad.2026.122284
PMCID: PMC13527671

Genes

HP1BP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical phenotypes of epigenetic biomarker positive versus biomarker negative postpartum depression.PMID 42476341Read ↗

Seeing the future: epigenetic biomarkers of postpartum depression.Semantic proximity Read ↗

Predictors of Postpartum Depression: A Comprehensive Review of the Last Decade of Evidence.Semantic proximity Read ↗

Early predictive biomarkers for postpartum depression point to a role for estrogen receptor signalingSemantic proximity Read ↗

Risk Factors for Postpartum Depression Based on Genetic and Epigenetic InteractionsSemantic proximity Read ↗

Epigenetic modifications appear in the human placenta following anxiety and depression during pregnancySemantic proximity Read ↗

Pilot validation of blood-based biomarkers during pregnancy and postpartum in women with prior or current depressionSemantic proximity Read ↗

Impact of Depression and Stress on Placental DNA Methylation in Ethnically Diverse Pregnant WomenSemantic proximity Read ↗

Distinct Genetic Profiles in Postpartum Depression With Different Trajectory of IllnessSemantic proximity Read ↗

Epigenetic Alterations and Prenatal Maternal DepressionSemantic proximity Read ↗

Risk Factors, Prognosis, Influence on the Offspring, and Genetic Architecture of Perinatal Depression Classified Based on the Depressive Symptom TrajectorySemantic proximity Read ↗

Placental DNA methylation marks are associated with maternal depressive symptoms during early pregnancySemantic proximity Read ↗

Association between maternal perinatal stress and depression and infant DNA methylation in the first year of lifeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.