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Article

Integrated GWAS and methylation analysis identify DNMT3A as an important regulator of growth in rabbits.

Genomics - 1 Sept 2026

Zhang Junsen, Zheng Kunkun, Tian Xinyang, Tang Tao, Zhou Junkun, Jia Xianbo, Sun Wenqiang, Chen Shi-Yi

Abstract excerpt

The parameters of individual growth curve can serve as pseudo-phenotype for genetic evaluation in livestock. In this study, we compared five nonlinear growth models using post-weaning body weights of 706 New Zealand White rabbits. Under the best-fitting model, two parameters of mature weight and maturity rate were subjected to GWAS through single-step genomic BLUP framework that integrated phenotypic records from...

Read the complete abstract on PubMed

Topics

Animals
Rabbits
DNA Methylation
DNA Methyltransferase 3A
Genome-Wide Association Study
DNA (Cytosine-5-)-Methyltransferases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Body Weight

Female

Cell Proliferation

Male

Source

Identifiers

PMID: 42463100
DOI: 10.1016/j.ygeno.2026.111295

Genes

DNMT3A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

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