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Phylogeographic dynamics of oropouche virus in the Colombian Amazon: Evolutionary insights in a climatic context.

PLoS neglected tropical diseases - 1 Jul 2026

Perez-Restrepo Laura S, Usuga Jaime, Vasquez Alejandro, Yepes Lina, Limonta Daniel, Knuese Cole, Moreno Isabel, Vargas Vanessa, Gonzalez-Ramirez Manuel, Berg Michael G, Rodgers Mary, Cloherty Gavin A, Hernandez-Ortiz Juan P, Osorio Jorge E

Abstract excerpt

BACKGROUND: In 2024, the largest RT-qPCR-confirmed outbreak of Oropouche virus (OROV) in 70 years occurred in the Brazilian Amazon, raising concerns about transmission and viral evolution in the neighboring Colombian Amazon Basin. This study characterizes the genetic diversity, epidemiology, and climatic context of OROV transmission during the 2024 outbreak in Leticia, Colombia. METHODOLOGY/PRINCIPAL FINDINGS:...

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Identifiers

PMID: 42447154
DOI: 10.1371/journal.pntd.0013810
PMCID: PMC13387556

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