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G550R Mutation of Histidine Kinase LtOs1 Confers High Fludioxonil Resistance in Lasiodiplodia theobromae from Avocado.

Journal of agricultural and food chemistry - 22 Jul 2026

Chen Bin, Hu Yuan, He Wen, Wang Mingyu, Liu Ruiqi, Li Guo, Li Jiawei, Li Xiujuan, Gu Aiguo, Yang Song, Chen Changyang, Song Xiushi, Shao Wenyong, Chen Changjun

Abstract excerpt

Lasiodiplodia theobromae is a destructive phytopathogenic fungus causing severe diseases across numerous crops, notably avocado dieback. While the phenylpyrrole fungicide fludioxonil (Flu) exhibits high efficacy against L. theobromae, its underlying resistance risk remains elusive. In the current study, the frequency distribution of Flu EC50 (mean EC50 = 0.0110 μg/mL) was established for 46 field isolates. In...

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Ascomycota
Dioxoles
Drug Resistance, Fungal
Fungicides, Industrial
Histidine Kinase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Docking Simulation

Protein Kinases

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PMID: 42444110
DOI: 10.1021/acs.jafc.6c04422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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