Article
HDA19-mediated deacetylation of histone H3.3 at lysines 27 and 36 regulates plant sensitivity to salt stress.
Proceedings of the National Academy of Sciences of the United States of America - 21 Jul 2026
Kotnik Florian, Ueda Minoru, Ito Akihiro, Ishida Junko, Takahashi Satoshi, Sakai Katsuyuki, Takagi Hiroshi, Seidel Julian, Abe Takahiro, Eirich Jürgen, Takahashi Shunji, Schwarzer Dirk, Seki Motoaki, Finkemeier Iris
Abstract excerpt
Plants survive extreme environments through rapid chromatin reprogramming, yet the epigenetic marks that confer stress resilience remain poorly understood. Histone deacetylase HDA19 is a key epigenetic regulator in Arabidopsis, and hda19-deficient mutants display tolerance to multiple abiotic stresses, including drought, heat, and salinity. Using lysine acetylome profiling, we identified a noncanonical K27/K36...
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