Genotype-directed therapy for non-small cell lung cancer diagnosed during pregnancy: A pooled analysis of seven cases from the Cancer and Pregnancy Registry with maternal and neonatal outcomes and review of the literature.

doi:10.1111/aogs.70303

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Article

Genotype-directed therapy for non-small cell lung cancer diagnosed during pregnancy: A pooled analysis of seven cases from the Cancer and Pregnancy Registry with maternal and neonatal outcomes and review of the literature.

Acta obstetricia et gynecologica Scandinavica - 1 Oct 2026

Firestone Reed, Gaughan John, Cardonick Elyce

Abstract excerpt

INTRODUCTION: Pregnant patients with cancer are routinely excluded from the clinical trials, limiting the evidence to guide the management of advanced malignancies during pregnancy. Data regarding maternal and neonatal outcomes associated with genotype-directed therapy for non-small cell lung cancer (NSCLC) during pregnancy remain limited. MATERIAL AND METHODS: We conducted a retrospective multicenter, pooled...

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Topics

Humans
Female
Pregnancy
Carcinoma, Non-Small-Cell Lung
Lung Neoplasms
Pregnancy Complications, Neoplastic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Retrospective Studies

Adult

Pregnancy Outcome

Registries

Infant, Newborn

Antineoplastic Agents

Genotype

Source

Open in PubMed Open full text

Identifiers

PMID: 42423550
DOI: 10.1111/aogs.70303
PMCID: PMC13394724

Genes

ALK
EGFR
ROS1

Provenance

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