Article
Genomic dissection of hoof and leg conformation in Swiss dairy cattle populations reveals polygenic architecture and a recessive HYAL1 nonsense variant affecting longevity in Holstein cattle.
Genetics, selection, evolution : GSE - 5 Jul 2026
Vasiljevic Stefan, Seefried Franz R, Widmer Sarah, Kadri Naveen K, Leonard Alexander S, He Qiongyu, Pausch Hubert, Besnard Florian, Capitan Aurélien, Drögemüller Cord, Jacinto Joana
Abstract excerpt
BACKGROUND: The genetic architecture of bovine hoof and leg conformation traits remains incompletely understood, particularly in dairy cattle and with respect to non-additive effects. Moreover, the limited genetic resolution of previous studies hampered the identification of candidate variants. This study aimed to investigate traits in Swiss Holstein (HO) and Brown Swiss (BS), comprising bone structure, heel...
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