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Article

Mutational spectrum of SLC26A4 and SLC26A5 associated with hereditary hearing loss in Moroccan families.

Human genomics - 1 Jul 2026

Idyahia Assia, Redouane Salaheddine, Chentoufi Fatima Ezzahra, Charoute Hicham, El Hamouchi Adil, Benrahma Houda, Barakat Abdelhamid

Abstract excerpt

BACKGROUND: The solute carrier family 26 (SLC26) encodes multifunctional anion transporters that mediate the transmembrane exchange of monovalent and divalent anions. While pathogenic variants in several SLC26 genes cause inherited disorders, only SLC26A4 and SLC26A5 have been linked to hereditary hearing loss (HHL). RESULTS: Exome sequencing performed in probands from nine unrelated Moroccan families with...

Read the complete abstract on PubMed

Topics

Humans
Sulfate Transporters
Morocco
Hearing Loss, Sensorineural
Female
Molecular Dynamics Simulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Pedigree

Mutation

Male

Mutation, Missense

Exome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 42387562
DOI: 10.1186/s40246-026-01010-0
PMCID: PMC13587510

Genes

SLC26A4
SLC26A5

Variants

Provenance

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