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Article

Rescue of Suprasellar Metastasis of EGFR-mutant NSCLC by Daily Osimertinib Re-escalation With Filgrastim Support.

In vivo (Athens, Greece) - 1 Jan 2026

Saito Shoichiro, Matsuda Shuichi, Nakamura Masato, Takahashi Rina, Yamamoto Ryo, Ibe Masaaki, Takamori Mikio, Kitazono Miyako

Abstract excerpt

BACKGROUND/AIM: Managing central nervous system (CNS) metastases of epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer can be challenging if dose-limiting toxicities prevent adequate drug exposure. CASE REPORT: We report the case of a 70-year-old woman with a suprasellar metastasis abutting the optic chiasm for whom radiotherapy was contraindicated. Although treatment with 80 mg...

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Identifiers

PMID: 42379747
DOI: 10.21873/invivo.14404
PMCID: PMC13321936

Genes

EGFR

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