Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HNF1B-MODY (MODY-5): a rare form of diabetes with multisystemic features-two case reports.

Frontiers in endocrinology - 1 Jan 2026

Carvalho Tânia, Lavrador Mariana, Saraiva Joana, Gomes Leonor

Abstract excerpt

Introduction: Maturity-Onset Diabetes of the Young (MODY) is a rare monogenic form of diabetes characterized by early onset and autosomal dominant inheritance. MODY-5, caused by HNF1B gene mutations, accounts for <5% of MODY cases and often presents with renal abnormalities and genitourinary malformations. Case presentation: We describe two patients with HNF1B-related MODY confirmed by heterozygous 17q12...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 2
Share to Hepatocyte Nuclear Factor 1-beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 42369057
DOI: 10.3389/fendo.2026.1841040
PMCID: PMC13293842

Genes

HNF1B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HNF1B-MODY (MODY-5): a rare form of diabetes with multisystemic features-two case reports.PMID 42369057Read ↗

Four Cases of Maturity Onset Diabetes of the Young (MODY) Type 5 Associated with Mutations in the Hepatocyte Nuclear Factor 1 Beta (HNF1B) Gene Presenting in a 13-Year-Old Boy and in Adult Men Aged 33, 34, and 35 Years in Poland.Semantic proximity Read ↗

Maturity-onset diabetes of the young (MODY): an update.Semantic proximity Read ↗

Maturity-onset diabetes of the young due to HNF1β variants (HNF1β-MODY): a 2-year follow-up study of six patients from a single diabetes center.Semantic proximity Read ↗

The Clinical Characteristics and Gene Mutations of Maturity-Onset Diabetes of the Young Type 5 in Sixty-One Patients.Semantic proximity Read ↗

Case Report: Beyond type 1 diabetes: a case of delayed MODY1 diagnosis and successful transition to sulfonylurea therapySemantic proximity Read ↗

Clinical spectrum associated with hepatocyte nuclear factor-1beta mutations.Semantic proximity Read ↗

Case Report: A case of HNF1B mutation patient with first presentation of diabetic ketosis.Semantic proximity Read ↗

Genetic Variants and Therapeutic Approaches in Maturity-Onset Diabetes of the Young: A Retrospective AnalysisSemantic proximity Read ↗

Pediatric Hepatocyte Nuclear Factor 1B (HNF1B) Disease: Diabetes and Endocrine Manifestations.Semantic proximity Read ↗

Genetics and Pathophysiology of Maturity-onset Diabetes of the Young (MODY): A Review of Current TrendsSemantic proximity Read ↗

17q12 Deletion Syndrome as a Rare Cause for Diabetes Mellitus Type MODY5Semantic proximity Read ↗

A rare combination of MODY5 and duodenal atresia in a patient: a case report.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.