Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Facial phenotypes in Alzheimer's disease: from neurobiology to artificial intelligence.

Alzheimer's research & therapy - 29 Jun 2026

Sun Wenshan, Xing Rong, Zhou Jian, Li Yong, Xu Gelin

Abstract excerpt

Facial analysis is increasingly being explored as a source of scalable behavioral signals relevant to Alzheimer's disease (AD) and AD-related cognitive impairment. In this narrative review, informed by a structured literature search, we summarize current evidence on the biological and behavioral basis of facial alterations in AD, with particular emphasis on affective expressivity, neuropsychiatric manifestations,...

Read the complete abstract on PubMed

Topics

Humans
Alzheimer Disease
Artificial Intelligence
Phenotype
Neurobiology
Facial Expression

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 42366401
DOI: 10.1186/s13195-026-02129-x
PMCID: PMC13591852

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Facial phenotypes in Alzheimer's disease: from neurobiology to artificial intelligence.PMID 42366401Read ↗

Facial expression recognition deficits in frontotemporal dementia and Alzheimer's disease: a meta-analytic investigation of effects of phenotypic variant, task modality, geographical region and symptomatic specificity.Semantic proximity Read ↗

Facial Expressions as a Nexus for Health AssessmentSemantic proximity Read ↗

THE DYNAMIC AFFECT RECOGNITION TEST: CONSTRUCTION AND VALIDATION IN NEURODEGENERATIVE SYNDROMESSemantic proximity Read ↗

A facial foundation model for multi-system biomarker and disease risk prediction with real-world mobile deploymentSemantic proximity Read ↗

COMPARING THE VALUE OF DYNAMIC VS. STATIC-IMAGE-BASED TESTS OF EMOTION RECOGNITION IN NEURODEGENERATIVE DISEASESSemantic proximity Read ↗

Potential of facial biomarkers for Alzheimer’s disease and Obstructive sleep apnea in Down syndrome and general populationSemantic proximity Read ↗

A Review of the Anatomical Basis of Facial Aging and Deep Learning-Based Recognition MethodsSemantic proximity Read ↗

Real-time facial emotion recognition deficits across the psychosis spectrum: A B-SNIP Study.Semantic proximity Read ↗

Remote clinical decision support tool for Parkinson's disease assessment using a novel approach that combines AI and clinical knowledgeSemantic proximity Read ↗

Multimodal Transformer-Based Fusion of Blood-Based and Digital Biomarkers for Explainable (XAI) Ultra-Early Alzheimer's Disease DetectionSemantic proximity Read ↗

Three-dimensional human facial morphologies as robust aging markersSemantic proximity Read ↗

Emotion perception in Behavior frontotemporal dementia and Alzheimer’s disease: the parahippocampal conundrumSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.