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Article

Exertional leg pain is associated with ıncreased disease activity and musculoskeletal ınvolvement, but not MEFV genotype, in familial Mediterranean fever.

Irish journal of medical science - 1 Aug 2026

Ösken Sibel, Çetin Çiğdem

Abstract excerpt

BACKGROUND: Familial Mediterranean fever (FMF) is characterized by recurrent inflammatory attacks and marked clinical heterogeneity. Exertional leg pain (ELP) is a common but underrecognized manifestation. AIMS: We aimed to evaluate the association of ELP with disease activity, inflammatory burden, and MEFV genotype distribution in patients with FMF. METHODS: In this retrospective cross-sectional study, FMF...

Read the complete abstract on PubMed

Topics

Humans
Familial Mediterranean Fever
Female
Male
Cross-Sectional Studies
Retrospective Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Adult

Pyrin

Genotype

Pain

C-Reactive Protein

Leg

Severity of Illness Index

Middle Aged

Colchicine

Blood Sedimentation

Source

Identifiers

PMID: 42360602
DOI: 10.1007/s11845-026-04511-y

Genes

MEFV
CRP

Provenance

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